Potato production in Uganda is being affected by rainfall fluctuations in both timing and amount, resulting into inadequate soil moisture availability and low productivity. Also, potato production is expanding into locations at lower altitudes, where drought is more common. Therefore, drought stress mitigation measures and coping mechanisms need to be devised to face future challenges of climate change, particularly in developing countries to ensure steady supply of adequate quantities of quality food. This study thus, aimed at characterizing new potato clones from CIP (International Potato Center) for tolerance to drought under Ugandan conditions.